Definition noun, plural: thrombopoieses (1) Thrombocytopoiesis, i.e. the process of producing thrombocytes (2) Thrombogenesis, i.e. the development of a thrombus or blood clot Supplement Thrombopoiesis might describe thrombocytopoiesis, which is a form of hematopoiesis) or to thrombogenesis, which is the formation of a blood clot (or thrombus). Hematopoiesis is the procedure of developing brand-new blood cellular elements in vertebrates. The process starts at the stem cells coming to be committed progenitor cells that inevitably develop into totally mature differentiated cells in blood. In humans, the cellular facets of the blood encompass red blood cells, white blood cells, and also thrombocytes. These cells are all acquired from the multipotent hematopoietic stem cells (HSCs). These have actually the capability to give rise to various mature blood cell kinds, such as erythrocytes, T cells, B cells, granulocytes, megakaryocytes, macrophperiods, and dendritic cells. Thrombopoiesis, in particular, is hematopoiesis that leads to the formation of thrombocytes. In this regard, below is the series of stperiods in thrombopoiesis: (1) A hemocytoblast provides climb to a common myeloid progenitor cell (CMP). (2) The CMP offers increase to CFU-Meg (or CFU-Mega, the swarm forming unit that leads to the development of megakaryocytes). (3) The CFU-Meg establishes right into a megakaryoblast. (4) The megakaryoblast establishes into a promegakaryocyte. (5) The promegakaryocyte establishes into a megakaryocyte. (6) The megakaryocyte is a mature cellular element in the blood responsible for the manufacturing of plateallows (or thrombocytes). The procedure in which the promegakaryocyte differentiates into a mature megakaryocyte is dubbed megakaryopoiesis. Thrombopoietin is the hormone that stimulates megakaryopoiesis. The hormone is developed by the liver and the kidney, and also encoded by the THPO gene. Word origin: thrombocyte + Greek poiesis (“to make”) See also:


megakaryopoiesis

Related form(s):

thrombopoietic (adjective)


Last updated on June 24th, 2021


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